PyClone-VI: scalable inference of clonal population structures using whole genome data
نویسندگان
چکیده
منابع مشابه
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The evolution of cancer genomes within a single tumor creates mixed cell populations with divergent somatic mutational landscapes. Inference of tumor subpopulations has been disproportionately focused on the assessment of somatic point mutations, whereas computational methods targeting evolutionary dynamics of copy number alterations (CNA) and loss of heterozygosity (LOH) in whole-genome sequen...
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ژورنال
عنوان ژورنال: BMC Bioinformatics
سال: 2020
ISSN: 1471-2105
DOI: 10.1186/s12859-020-03919-2